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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CANX
All Species:
41.82
Human Site:
T171
Identified Species:
61.33
UniProt:
P27824
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27824
NP_001019820.1
592
67568
T171
Y
V
K
L
L
S
K
T
P
E
L
N
L
D
Q
Chimpanzee
Pan troglodytes
XP_001151304
592
67554
T171
Y
V
K
L
L
S
K
T
P
E
L
N
L
D
Q
Rhesus Macaque
Macaca mulatta
XP_001101429
592
67582
T171
Y
V
K
L
L
S
K
T
P
E
L
N
L
D
Q
Dog
Lupus familis
XP_533285
610
69806
T162
Y
I
K
L
L
A
D
T
D
G
L
N
L
E
N
Cat
Felis silvestris
Mouse
Mus musculus
P35564
591
67259
T172
Y
V
K
L
L
S
K
T
A
E
L
S
L
D
Q
Rat
Rattus norvegicus
P35565
591
67236
T172
Y
V
K
L
L
S
K
T
S
E
L
N
L
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506871
598
67609
T174
Y
V
K
L
L
S
R
T
P
E
L
N
L
D
Q
Chicken
Gallus gallus
NP_001025791
599
68090
T172
Y
V
K
L
L
S
K
T
P
E
L
N
L
D
Q
Frog
Xenopus laevis
NP_001080326
611
69964
T183
Y
V
K
L
L
S
K
T
Q
E
Q
K
P
E
Q
Zebra Danio
Brachydanio rerio
NP_998613
600
67856
T179
Y
V
K
L
L
S
Q
T
P
D
L
D
L
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
L112
C
G
G
G
Y
V
K
L
F
D
C
S
L
D
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34652
619
69189
G163
Y
L
K
L
L
S
E
G
A
E
K
D
L
A
N
Sea Urchin
Strong. purpuratus
XP_791226
591
66512
T166
Y
V
K
L
L
T
D
T
P
D
L
S
L
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
K126
L
G
G
D
V
D
Q
K
T
L
G
G
D
T
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P29402
530
60468
K154
N
K
V
H
F
I
L
K
H
K
N
P
K
S
G
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
V168
C
A
P
E
I
N
G
V
Q
F
A
I
N
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.6
59.1
N.A.
93
93.5
N.A.
85.7
82.8
78.2
70.8
N.A.
31.7
N.A.
40.5
53.7
Protein Similarity:
100
99.8
99.4
75.2
N.A.
96.6
97.4
N.A.
93.1
90.8
86.2
84.1
N.A.
44.7
N.A.
58.9
69.7
P-Site Identity:
100
100
100
53.3
N.A.
86.6
93.3
N.A.
93.3
100
66.6
66.6
N.A.
26.6
N.A.
46.6
66.6
P-Site Similarity:
100
100
100
73.3
N.A.
93.3
93.3
N.A.
100
100
73.3
100
N.A.
40
N.A.
66.6
86.6
Percent
Protein Identity:
N.A.
29.3
N.A.
40
25.6
N.A.
Protein Similarity:
N.A.
44.4
N.A.
53.5
41.2
N.A.
P-Site Identity:
N.A.
0
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
7
0
0
13
0
7
0
0
7
0
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
7
0
7
13
0
7
19
0
13
7
57
0
% D
% Glu:
0
0
0
7
0
0
7
0
0
57
0
0
0
19
7
% E
% Phe:
0
0
0
0
7
0
0
0
7
7
0
0
0
0
0
% F
% Gly:
0
13
13
7
0
0
7
7
0
7
7
7
0
0
7
% G
% His:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
7
0
0
0
0
0
7
0
0
0
% I
% Lys:
0
7
75
0
0
0
50
13
0
7
7
7
7
7
0
% K
% Leu:
7
7
0
75
75
0
7
7
0
7
63
0
75
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
7
0
0
0
0
7
44
7
0
13
% N
% Pro:
0
0
7
0
0
0
0
0
44
0
0
7
7
0
0
% P
% Gln:
0
0
0
0
0
0
13
0
13
0
7
0
0
0
57
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
63
0
0
7
0
0
19
0
7
13
% S
% Thr:
0
0
0
0
0
7
0
69
7
0
0
0
0
7
0
% T
% Val:
0
63
7
0
7
7
0
7
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
75
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _